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Evaluation of bacterial co-infections of the respiratory tract in COVID-19 patients admitted to ICU.

Authors: Ehsan Sharifipour , Saeed Shams , Mohammad Esmkhani , Javad Khodadadi , Reza Fotouhi-Ardakani

DOI: 10.1186/S12879-020-05374-Z

Keywords:

Description: COVID-19 is known as a new viral infection. Viral-bacterial co-infections are one of the biggest medical concerns, resulting in increased mortality rates. To date, few studies have investigated bacterial superinfections patients. Hence, we designed current study on patients admitted to ICUs. Nineteen our ICUs were enrolled this study. detect COVID-19, reverse transcription real-time polymerase chain reaction was performed. Endotracheal aspirate samples also collected and cultured different media support growth bacteria. After incubation, formed colonies identified using Gram staining other biochemical tests. Antimicrobial susceptibility testing carried out based CLSI recommendations. Of nineteen patients, 11 (58%) male 8 (42%) female, with mean age ~ 67 years old. The average ICU length stay ~ 15 days at end study, 18 cases (95%) expired only 1 case (5%) discharged. In total, all found positive for infections, including seventeen Acinetobacter baumannii (90%) two Staphylococcus aureus (10%) strains. There no difference bacteria species detected any sampling points. Seventeen 17 strains resistant evaluated antibiotics. No metallo-beta-lactamases -producing strain found. One isolates methicillin-resistant isolated from patient who died, while another susceptible tested drugs methicillin-sensitive aureus. Our findings emphasize concern superinfection due Consequently, it important pay attention critical COVID-19.

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