Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients. Matthew K. Tobin , Kianna Musaraca , Ahmed Disouky , Aashutosh Shetti , Abdullah Bheri , William G. Honer , Namhee Kim , Robert J. Dawe , David A. Bennett , Konstantinos Arfanakis , Orly Lazarov - Cell Stem Cell, 2019 | | 134 |
Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility. Huaigeng Xu , Bo Wang , Miyuki Ono , Akihiro Kagita , Kaho Fujii , Noriko Sasakawa , Tatsuki Ueda , Peter Gee , Misato Nishikawa , Masaki Nomura , Fumiyo Kitaoka , Tomoko Takahashi , Keisuke Okita , Yoshinori Yoshida , Shin Kaneko , Akitsu Hotta - Cell Stem Cell, 2019 | | 126 |
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SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response Jessie Huang , Adam J. Hume , Kristine M. Abo , Rhiannon B. Werder , Carlos Villacorta-Martin , Konstantinos-Dionysios Alysandratos , Mary Lou Beermann , Chantelle Simone-Roach , Jonathan Lindstrom-Vautrin , Judith Olejnik , Ellen L. Suder , Esther Bullitt , Anne Hinds , Arjun Sharma , Markus Bosmann , Ruobing Wang , Finn Hawkins , Eric J. Burks , Mohsan Saeed , Andrew A. Wilson , Elke Mühlberger , Darrell N. Kotton - Cell Stem Cell, 2020 | | 55 |
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Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response Giulia Schiroli , Anastasia Conti , Samuele Ferrari , Lucrezia della Volpe , Aurelien Jacob , Luisa Albano , Stefano Beretta , Andrea Calabria , Valentina Vavassori , Patrizia Gasparini , Eralda Salataj , Delphine Ndiaye-Lobry , Chiara Brombin , Julie Chaumeil , Eugenio Montini , Ivan Merelli , Pietro Genovese , Luigi Naldini , Raffaella Di Micco - Cell Stem Cell, 2019 | | 97 |
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons. Rik van der Kant , Vanessa F. Langness , Cheryl M. Herrera , Daniel A. Williams , Lauren K. Fong , Yves Leestemaker , Evelyne Steenvoorden , Kevin D. Rynearson , Jos F. Brouwers , J. Bernd Helms , Huib Ovaa , Martin Giera , Steven L. Wagner , Anne G. Bang , Lawrence S.B. Goldstein - Cell Stem Cell, 2019 | | 83 |
Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway. Richard J. Mills , Benjamin L. Parker , Gregory A. Quaife-Ryan , Holly K. Voges , Elise J. Needham , Aurelie Bornot , Mei Ding , Henrik Andersson , Magnus Polla , David A. Elliott , Lauren Drowley , Maryam Clausen , Alleyn T. Plowright , Ian P. Barrett , Qing-Dong Wang , David E. James , Enzo R. Porrello , James E. Hudson - Cell Stem Cell, 2019 | | 73 |
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Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2. Jeonghwan Youk , Taewoo Kim , Kelly V. Evans , Young-Il Jeong , Yongsuk Hur , Seon Pyo Hong , Je Hyoung Kim , Kijong Yi , Su Yeon Kim , Kwon Joong Na , Thomas Bleazard , Ho Min Kim , Mick Fellows , Krishnaa T. Mahbubani , Kourosh Saeb-Parsy , Seon Young Kim , Young Tae Kim , Gou Young Koh , Byeong-Sun Choi , Young Seok Ju , Joo-Hyeon Lee - Cell Stem Cell, 2020 | | 28 |
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Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration. Brian J. Pepe-Mooney , Michael T. Dill , Anna Alemany , Jose Ordovas-Montanes , Yuki Matsushita , Anuradha Rao , Anushna Sen , Makoto Miyazaki , Sayeepriyadarshini Anakk , Paul A. Dawson , Noriaki Ono , Alex K. Shalek , Alexander van Oudenaarden , Fernando D. Camargo - Cell Stem Cell, 2019 | | 66 |
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Capturing human trophoblast development with naive pluripotent stem cells in vitro Knut Woltjen , Mitinori Saitou , Chizuru Iwatani , Masaki Mandai , Eiji Kondoh , Katsunori Semi , Shingo Io , Hideaki Tsuchiya , Yasuhiro Takashima , Yoji Kojima , Shin Kaneko , Ikuhiro Okamoto , Takuya Yamamoto , Nobuhiro Morone , Atsutaka Minagawa , Tomonori Nakamura , Yoshiki Iemura , Mio Kabata , Bo Wang , Belinda Kaswandy - Cell Stem Cell, 2021 | | 2 |
The Dynamic Transcriptional Cell Atlas of Testis Development during Human Puberty Jingtao Guo , Xichen Nie , Maria Giebler , Hana Mlcochova , Yueqi Wang , Edward J. Grow , Robin Kim , Melissa Tharmalingam , Gabriele Matilionyte , Cecilia Lindskog , Douglas T. Carrell , Rod T. Mitchell , Anne Goriely , James M. Hotaling , Bradley R. Cairns - Cell Stem Cell, 2020 | | 38 |
Ascl2-Dependent Cell Dedifferentiation Drives Regeneration of Ablated Intestinal Stem Cells Kazutaka Murata , Unmesh Jadhav , Shariq Madha , Johan van Es , Justin Dean , Alessia Cavazza , Kai Wucherpfennig , Franziska Michor , Hans Clevers , Ramesh A. Shivdasani - Cell Stem Cell, 2020 | | 42 |
CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank Maarten H. Geurts , Eyleen de Poel , Gimano D. Amatngalim , Rurika Oka , Fleur M. Meijers , Evelien Kruisselbrink , Peter van Mourik , Gitte Berkers , Karin M. de Winter-de Groot , Sabine Michel , Danya Muilwijk , Bente L. Aalbers , Jasper Mullenders , Sylvia F. Boj , Sylvia W.F. Suen , Jesse E. Brunsveld , Hettie M. Janssens , Marcus A. Mall , Simon Y. Graeber , Ruben van Boxtel , Cornelis K. van der Ent , Jeffrey M. Beekman , Hans Clevers - Cell Stem Cell, 2020 | | 40 |
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